Program Goals

This program is designed to improve clinical awareness of spinal muscular atrophy (SMA), the leading inherited cause of infant mortality. Historical and updated findings concerning the syndrome and the causative recessive gene survival of motor neuron (SMN1) will be presented. The potential influence that SMN2 has on the severity of the disease progression will also be discussed. Carrier testing and prenatal diagnosis will be discussed along with considerations for population carrier screening.

Target Audience

Obstetricians/Gynecologists, Ph.D. Clinical Geneticists, M.D. Medical Geneticists, Genetic Counselors, Pediatricians, Nurses, Mental Health Specialists, Laboratory Professionals, and related healthcare professionals interested or involved in the clinical relevance of spinal muscular atrophy.

Educational Objectives

Upon completion of this activity, participants should be able to:

1. Identify the clinical manifestations associated with SMA, including SMA type I, the most common and severe form of the disease.
2. Discuss test methodologies for carrier testing and diagnostic testing, including benefits and limitations of each methodology.
3. Specify the inheritance pattern and carrier frequency for SMA.
4. Explain the general principles of a woman's risk to her offspring.

Faculty

Kathryn J. Swoboda, MD
Associate Professor, Neurology and Pediatrics
Director, Pediatric Motor Disorders Research Program
University of Utah School of Medicine
Salt Lake City, Utah

Educational Activity Agenda

- 01 minutes: Welcome & Introduction
- 45 minutes: Faculty Presentation
- 10 minutes: Q&A Session
- 04 minutes: Conclusion, Evaluation & Post Test

Disclosure

Global Education Group adheres to the ACCME Essential Areas and Policies, including the Standards for Commercial Support regarding industry support of continuing medical education. In order to resolve any identified conflicts of interest, disclosure information is provided during the planning process to ensure resolution of any identified conflicts. Disclosure of faculty and commercial relationships as well as the discussion of unlabeled/investigational use of any drug, device or procedure by the faculty, are made known below.

Faculty Disclosures

The faculty reported the following financial relationships or relationships to products or devices they or their spouse / life partner have with commercial interests related to the content of this P.A.C.E. accredited activity:

Disclosure of Unlabeled Use / Investigational Use

In this activity, the following faculty discloses that they may discuss the unlabeled or investigational use of drugs, devices or procedures in their discussions regarding hepatitis therapy:

•  Kathryn J. Swoboda, MD

Planners and Managers

Employees of Global Education Group, the accredited provider for this activity, have disclosed that they have no significant financial relationships.

Employees of Dane Garvin Ltd., the joint sponsor for this activity, have disclosed they have no significant financial relationships.

CME (ACCME) Accreditation Statement

This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of Global Education Group (Global) and Dane Garvin Ltd. (DGL). Global is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation - Physician, CME

Global Education Group designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credit(s) ™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

For any questions concerning the accreditation of this activity, please contact Global Education Group at:
303-395-1782 or through e-mail at inquire@globaleducationgroup.com

How to Obtain CME Credit

ACCREDITATION FOR THIS ACTIVITY HAS EXPIRED

Viewers are expected to visit all presentations before attempting to take the test and activity evaluation. Successful completion will lead to the issuance of a certificate for 1.0 AMA PRA Category 1 Credit(s)™. To receive credit, the course must be completed before September 15, 2009.

Participants who have already received continuing education credit for attending the July 28, 2008 live webcast are not eligible to receive additional credit for this enduring online activity.

Participation in this activity should be completed in approximately 1.0 hours. Please follow these steps in order to receive CME credit for viewing the webcast:

• Read all of the CME accreditation information above.
• View the complete webcast program.
• Click on the link to apply for CME credits.
• Complete the online registration (registration is free).
• Complete the online test and/or evaluation. Participants must receive a test score of at least 75% and answer all evaluation questions to receive a certificate.

After successfully completing the online test and evaluation, your application will be processed by the CME provider and your certificate will be sent to you. Please allow 3-4 weeks for this process.

Should you have any CME questions regarding this activity, please contact:

Global Education Group
5575 S. Sycamore Street, Suite 200
Littleton, CO 80128
Phone: 303-395-1782
Fax: 303-648-5311
Email: inquire@globaleducationgroup.com
Web: www.globaleducationgroup.com

Credit Designation - Lab Professional, P.A.C.E.^®

The American Society for Clinical Laboratory Sciences Professional Acknowledgment for Continuing Education (P.A.C.E.^®) Program will provide 1.0 contact hour of credit.

How to Obtain P.A.C.E.^® Credit

ACCREDITATION FOR THIS ACTIVITY HAS EXPIRED

Viewers are expected to complete the presentation before attempting to submit contact information and the session evaluation. Successful completion will lead to the issuance of a certificate for 1.0 contact hour of P.A.C.E.^® approved continuing education. To receive credit, the course must be completed before September 15, 2009.

Participants who have already received P.A.C.E.^® credit for attending the July 28, 2008 live webcast are not eligible to receive additional credit for this enduring online activity.

Participation in this activity should be completed in approximately 1.0 hours. Please follow these steps in order to receive P.A.C.E.^® credit for viewing the webcast:

• Read all of the information above.
• View the complete webcast program.
• Click on the “Lab Professional” link to apply for P.A.C.E.^® credit
• Complete the online registration (registration is free).
• Complete the online test and/or evaluation. Participants must receive a test score of at least 70% and answer all evaluation questions to receive P.A.C.E.^® credit.
• After successfully completion of this process, you will be redirected to the ASCLS CE Organizer where you may create and print an official ASCLS P.A.C.E.^® certificate based on your attendance and completion of this ASCLS-sponsored P.A.C.E.^® approved learning activity.

Should you have any P.A.C.E.^® questions regarding this activity, please contact:

ASCLS P.A.C.E.^®
1861 International Drive, Suite 200
Tysons Corner, VA 22102
Ph: 571-748-3776
Fx: 571-354-7576
http://www.ascls.org/

For technical difficulties, please consult our Technical Instructions.

Release and Expiration

Release Date: September 15, 2008
Expiration Date: September 15, 2009

Fee Information

There is no fee for this educational activity.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and Dane Garvin Ltd. do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

The opinions expressed in this educational activity are those of the faculty and do not reflect the views of Global Education Group and/or Dane Garvin, Ltd. This educational activity may discuss off-label and/or investigational uses and dosages for therapeutic products/procedures that have not been approved by the United States Food and Drug Administration (FDA). Global Education Group and Dane Garvin, Ltd. do not recommend the use of any product/procedure outside of the labeled indications. A qualified health care professional should be consulted before using any therapeutic product/procedure discussed. All readers and continuing education participants should verify all information and data before treating patients or employing any therapies described in this continuing education activity. Please refer to the official prescribing information for each product/procedures for approved indication, contraindications, and warnings.

Policy on Privacy and Confidentiality

Global Education Group (Global) protects the privacy of personal and other information regarding participants, educational partners, and joint sponsors. Global and our joint sponsors will not release personally identifiable information to a third party without the individual's consent, except such information as is required for reporting purposes to the appropriate accrediting agency.

Global Education Group and Dane Garvin, Ltd. maintain physical, electronic and procedural safeguards that comply with federal regulations to guard your nonpublic personal information.

Medium Used

This program has been made available online.

"Spinal Muscular Atrophy"

System Requirements

To view this educational activity you will need a web browser with Javascript and either Flash or HTML5 enabled.  Nearly all modern web browsers will work.

Commercial Support Statement

  This activity is supported by an educational grant from Genzyme, Inc.

Copyright

Copyright © September 15, 2008 – September 15, 2009. Dane Garvin, Ltd. All Rights Reserved. Permission for accreditation is granted to Global Education Group (Global) and American Society for Clinical Laboratory Sciences.